Polash Ahsan Habib
I am enrolled as a doctoral student at Radiation Genetics Lab of Graduate School of Medicine, Kyoto University.
Although my lab focuses on Genotoxicity and Carcinogenesis, my research focus is including, but not limited to, Cheminformatics/Chemoinformatics, Computational Biology, Medicinal Chemistry, Life Science Informatics and Immunoinformatics.
I have been studying application of Artificial Intelligence for drug discovery and chemical toxicity for my doctoral research.
I often employ computational resources to study kinase inhibitors and to predict toxicity of chemical compounds.
Very often Machine Learning (ML) algorithms are applied in my working strategies to elucidate the Structure Activity Relationship (SAR) of chemical compounds and I am eager to deconvolute the decision making processes by ML.
I am highly knowledgable about NGS data (ChIP-seq/RNA-seq/CAGE data) analysis.
I have analyzed transcriptomics data to evaluate the effect of small molecules to cell line models so that their role in DNA repair dynamics and carcinogenesis is understood. I am familiar with public databases like TCGA, ENCODE etc.
By training I am a molecular biologist. I have experiences with cell biology experiemnts, i.e clonogenic cell survival assays, DNA repair kinetics etc.
As a data vizualization enthuast I often discuss biological data handling and representation with my collleagues.